Brain & Cognitive

After decades of prohibition, psychedelic-assisted therapy is producing the most exciting results in psychiatry in a generation

The NGF-stimulating mushroom with real in vitro data, one landmark clinical trial, and a supplement industry that has run the story much further than the human evidence supports

FDA-approved clinical VNS for epilepsy and depression exists alongside a TikTok trend of "vagus nerve resets" — they are completely different interventions, and conflating them is how wellness culture works at its most misleading

A single human RCT with 44 participants is the entire clinical evidence base for a $500 million supplement market — and the patent holder funds most of the research

A flavone found in chamomile tea that became a $50M+ supplement market through a single podcast recommendation — with zero human RCTs on isolated supplementation, an arbitrary dose pulled from nowhere, and an entire industry built on the extrapolation from chamomile extract research to a compound that may not survive oral digestion intact