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Energy & Metabolism

Metabolic interventions, mitochondrial support, and approaches to fatigue, insulin resistance, and metabolic dysfunction — grounded in mechanism and data.

Energy & Metabolism

Intermittent Fasting for Type 2 Diabetes

A dietary pattern older than agriculture is producing results that surprise even the endocrinologists studying it

Clinical trials, mechanistic research, and head-to-head comparisons of intermittent fasting protocols for type 2 diabetes.

Energy & Metabolism

Mitochondrial Dysfunction

When your cells' power plants fail — and mainstream medicine is just beginning to understand why

CoQ10 and PQQ supplementation trial data, the link between mitochondrial dysfunction and chronic disease, and what peer-reviewed research actually establishes.

Energy & Metabolism

Taurine

The 2023 Science paper changed everything — but most of the longevity hype is getting ahead of the data

The Singh et al. landmark study, cardiovascular protection data, neurological benefits research, and a clear-eyed assessment of what extrapolating to human s…

Energy & Metabolism

Cold Exposure Therapy

Cold plunges went from biohacker niche to mainstream wellness trend — the dopamine data is real, the recovery claims are complicated, and the safety conversation is overdue

The Søberg 2021 dopamine study, Buijze 2016 cold shower RCT, Cochrane cryotherapy reviews, brown adipose tissue activation research, and the norepinephrine m…

Energy & Metabolism

Berberine

TikTok called it "nature's Ozempic" — the clinical evidence is older, more nuanced, and more interesting than the viral narrative suggests

Yin et al. (2008) meta-analysis of 14 RCTs (n=1,068) showed berberine reduces fasting glucose by -0.9 mmol/L and HbA1c by -0.72% versus placebo. Zhang et al.…

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